60%
Highest listed pathwayThe 60% level applies to Addison's disease with four or more Addisonian crises documented during the past year.
What separates the next level: Three crises (rather than four or more) reaches only the 40 percent tier, even if five or more episodes are also documented -- four or more crises is this tier's own independent threshold.
Review CFR criteria, examples, and evidence
- Official CFR language
- Four or more crises during the past year -- 60 percent. Note (1): An Addisonian "crisis" consists of the rapid onset of peripheral vascular collapse (with acute hypotension and shock), with findings that may include: anorexia; nausea; vomiting; dehydration; profound weakness; pain in abdomen, legs, and back; fever; apathy, and depressed mentation with possible progression to coma, renal shutdown, and death.
- Qualification explanation
- Reached when the documented record shows four or more Addisonian crises, as Note (1) defines a crisis, within the past year.
- Examples
- Records documenting four or more distinct episodes of rapid-onset peripheral vascular collapse with acute hypotension and shock within the past 12 months.
- Medical evidence
- Endocrinology treatment records; Emergency or hospitalization records documenting each crisis; Cortisol and ACTH stimulation test results confirming adrenocortical insufficiency
- Functional impact examples
- Four or more hospitalizations or emergency treatments for acute adrenal crisis within the past year.
- Common misconceptions
- A general history of Addison's disease does not by itself reach 60 percent -- the count of Note (1)-defined crises within the past year is what this tier requires.
- Related topics
- Addisonian crisis; adrenocortical insufficiency; past-year crisis count
- Source context
- 38 CFR 4.119; 7911; Confirmed via Cornell LII, eCFR versioner API, and govinfo XML, cross-checked. The Federal Register final rule 2017-23044 (89 FR ... published Nov. 2, 2017) revised DC 7907-7919 including DC 7911; no amendment since found via a direct Federal Register API search for 38 CFR 4.119 documents.